Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART |
| Enrichment Score (ES) | -0.609005 |
| Normalized Enrichment Score (NES) | -1.5132906 |
| Nominal p-value | 0.027079303 |
| FDR q-value | 0.6484216 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PDE3B | 2030563 | 1905 | 0.562 | -0.0426 | No | ||
| 2 | CAMK2B | 2760041 | 2904 | 0.305 | -0.0638 | No | ||
| 3 | PDE2A | 6100504 | 3242 | 0.247 | -0.0557 | No | ||
| 4 | FLT1 | 3830167 4920438 | 3565 | 0.205 | -0.0512 | No | ||
| 5 | BDKRB2 | 4780706 | 4684 | 0.113 | -0.0994 | No | ||
| 6 | GUCY1B2 | 2120128 | 5251 | 0.084 | -0.1209 | No | ||
| 7 | RYR2 | 2760671 | 5731 | 0.066 | -0.1396 | No | ||
| 8 | PIK3CA | 6220129 | 6193 | 0.053 | -0.1588 | No | ||
| 9 | FLT4 | 1240292 6350707 | 6879 | 0.038 | -0.1916 | No | ||
| 10 | CHRM1 | 4280619 | 7248 | 0.030 | -0.2082 | No | ||
| 11 | NOS3 | 630152 670465 | 7547 | 0.025 | -0.2216 | No | ||
| 12 | GUCY1B3 | 2970020 | 8591 | 0.009 | -0.2768 | No | ||
| 13 | PIK3R1 | 4730671 | 8630 | 0.008 | -0.2779 | No | ||
| 14 | GUCY1A2 | 1660441 | 8656 | 0.008 | -0.2784 | No | ||
| 15 | CHRNA1 | 1170025 3610364 5220292 | 9059 | 0.003 | -0.2997 | No | ||
| 16 | AKT1 | 5290746 | 9115 | 0.002 | -0.3025 | No | ||
| 17 | PRKAR2B | 3130593 5220577 | 9324 | -0.001 | -0.3136 | No | ||
| 18 | KNG1 | 6400576 6770347 | 10116 | -0.012 | -0.3549 | No | ||
| 19 | CAV1 | 870025 | 10151 | -0.013 | -0.3554 | No | ||
| 20 | KDR | 3610286 | 10384 | -0.016 | -0.3662 | No | ||
| 21 | TNNI1 | 3710040 | 11518 | -0.034 | -0.4235 | No | ||
| 22 | PRKG1 | 4120671 | 11606 | -0.036 | -0.4244 | No | ||
| 23 | GUCY1A3 | 110253 2640735 4070037 | 12143 | -0.047 | -0.4483 | No | ||
| 24 | GUCY2F | 2450309 | 12607 | -0.058 | -0.4670 | No | ||
| 25 | PRKAR2A | 2340136 | 12700 | -0.061 | -0.4654 | No | ||
| 26 | GNGT1 | 5220156 | 12795 | -0.064 | -0.4637 | No | ||
| 27 | PRKAR1B | 6130411 | 13066 | -0.072 | -0.4706 | No | ||
| 28 | PDE3A | 380068 | 13079 | -0.073 | -0.4635 | No | ||
| 29 | HSP90AA1 | 4560041 5220133 2120722 | 13851 | -0.104 | -0.4939 | No | ||
| 30 | GNAQ | 430670 4210131 5900736 | 13945 | -0.110 | -0.4872 | No | ||
| 31 | SLC7A1 | 2450193 2710241 | 14147 | -0.122 | -0.4850 | No | ||
| 32 | PLCG1 | 6020369 | 14633 | -0.160 | -0.4940 | No | ||
| 33 | PRKG2 | 1110465 | 14756 | -0.170 | -0.4825 | No | ||
| 34 | GUCY2C | 110411 6110156 | 15436 | -0.259 | -0.4914 | No | ||
| 35 | PRKACB | 4210170 | 17621 | -1.021 | -0.5002 | Yes | ||
| 36 | VEGFA | 2940338 | 17798 | -1.149 | -0.3873 | Yes | ||
| 37 | PDPK1 | 6650168 | 17818 | -1.163 | -0.2644 | Yes | ||
| 38 | PRKAR1A | 3450369 | 18084 | -1.376 | -0.1320 | Yes | ||
| 39 | GNB1 | 2120397 | 18190 | -1.508 | 0.0229 | Yes |
